Wednesday’s biggest gaining and declining stocks

Palm Beach, FL 6/6/12 (StreetBeat) -- Here are some of the most active stocks in U.S. trading this Wednesday:

Gainers

Ancestry.com (Nasdaq:ACOM +11.10%) shares added 10%. Bloomberg News, citing people familiar with the matter, reports that the company is mulling selling itself and has hired Frank Quattrone’s Qatalyst Partners LLC to find buyers.

BioSante Pharmaceuticals (Nasdaq:BPAX +8.21%) rose 7.7%. The firm is scheduled to present at an investment conference sponsored by Jefferies & Co. later Wednesday..

Shares of Amyris (Nasdaq:AMRS +17.17%) rose about 16% on Wednesday. The move follows a big gain the previous session after the company, a biofuels maker, said its jetfuel will be used as part of demonstration project at a U.N conference in Brazil later this month.

Decliners

Mattress Firm (Nasdaq:MFRM -32.43%) shares fell 31%. The company’s quarterly sales missed estimates.

Mitcham Industries Inc. (Nasdaq:MIND -6.72%) shares fell 6.7%. The company said late Tuesday that its first-quarter earnings rose 39%, but they came in under Wall Street expectations. Revenue and profit margins were also weaker than expected.

Select Comfort Corp. (Nasdaq:SCSS -19.49%) shares dropped 22% on Wednesday. A day earlier the company unveiled management changes.

Tempur-Pedic International Inc. (NYSE:TPX -47.29%) shares fell 46% after the company cut its earnings outlook.

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Big Selloff Today for Tempur-Pedic (TPX) After Lower Guidance

Naples, FL 4/20/2012 (StreetBeat) -- Mattress maker Tempur-Pedic (TPX) yesterday after the close reported Q1 EPS of 86c, compared with analysts' consensus estimate of 84c. However, the company's revenue was slightly lower than expected. Moreover, the mattress maker provided FY12 EPS guidance of $3.80-$3.95, versus the consensus estimate of $3.97.

The company's full-year revenue estimate was also lower than expected. On a positive note, Tempur-Pedic said that its advertising which ramped up in Q1 has been yielding positive results, especially in international markets. Further, the company said it was pleased with the initial performance of its new Simplicity mattress.

In a note to investors today, Oppenheimer recommended buying Tempur-Pedic's stock on weakness. The firm still expects the company to benefit from the ongoing transition to specialty bedding technologies. In mid-morning trading, Tempur-Pedic sank $18.52, or 22.11%, to $65.23. Select Comfort (SCSS), a bed manufacturer, also fell significantly.

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