
Metabolix shares were down 56 percent to $2.64 in early trade on Friday, making it the top percentage loser on the Nasdaq.
Jefferies downgraded the company -- which makes plastics, chemicals and energy from non-food crops like switchgrass -- to "hold" from "buy," saying the termination illustrates "one of the challenges faced by the capital-intensive renewables sector."
On Thursday, ADM said it will end its relationship with Metabolix as projected financial returns were "too uncertain."
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